Sodium cholate is one of two major bile acids produced by the liver where it is synthesized from cholesterol. Of the two major bile acids, cholate derivatives represent approximately eighty percent of all bile acids. These derivatives are made from cholyl-CoA which forms a conjugate with either glycine, or taurine, yielding glycocholic and taurocholic acid respectively.
Sodium cholate is a white crystalline substance insoluble in water (soluble in alcohol and acetic acid), with a melting point of 200-201 °C. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid.
Usages:
Preparation of bacterial culture medium, instead of cephalin cholesterol flocculation test for protein analysis.
Lysate sodium deoxycholate and the original role of sodium alum
The former is ionic detergent, which is the inhibition of tyrosine phosphatase activity.
CAS: 302-95-4
Molecular formula: C24H39O4Na
Molecular Weight: 414.55
Purity :> 99%
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